APPENDIX C

I. DEFINITION OF TERMS

• The only absolute way to prevent infection or transmission of HIV through sexual contact is to not have oral, anal, or vaginal intercourse with persons potentially infected (i.e., sex with self or no sex).
• SAFEST SEX: mutual masturbation, kissing, body rubbing (frottage) erotic conversation (e.g., phone sex), unshared sex toys (wash hands before and after sex).
• POSSIBLY SAFE SEX: condoms^* for oral, anal and vaginal sex. Condoms should be latex only, put on before penetration.
• UNSAFE SEX: oral, vaginal, or anal intercourse without condom^*; vaginal, anal sex without condom where partner withdraws before ejaculation; fisting, rimming, shared sex toys.
• For purposes of AVEG trials, we will define unprotected oral intercourse with an HIV+ partner as unsafe sex, with an unknown partner as possibly safe sex.
• HIGHER RISK-ASSOCIATED STD: The following STDs are considered associated with higher risk sexual behavior:
  • - Neisseria gonorrhea
  • - Non-gonococcal urethritis
  • - Chlamydia trachomatis
  • - Newly acquired infection with herpes simplex virus, Treponema pallidum (syphilis), Trichomonas vaginalis
  • - Newly acquired mucopurulent cervicitis, acute epididymitis, acute proctitis
  • - Pelvic inflammatory disease
  • - Lymphogranuloma venereum
  • - Chancroid
  • - Sexually acquired Hepatitis B
• The following STDs are not considered associated with higher risk sexual behavior:
  • - Scabies
  • - Yeast
  • - Pediculosis pubis
  • - Bacterial vaginosis
  • - Anogenital warts

  ^* Substitute dental dam or equivalent in cases of oral-genital sex

II. RISK CATEGORIES

RISK DEFINITION A:

EITHER ALL OF THE FOLLOWING

1. No newly acquired higher risk associated STD in the last 6 months
2. No possibly safe or unsafe sex with a known HIV+ individual or an active injection drug user in the past 6 months
3. No unsafe sexual activity
4. Possibly safe sexual activity with two or fewer partners within the last 6 months
5. No injection drug use

OR BOTH OF THE FOLLOWING

1. Mutually monogamous relationship with a known or presumed HIV seronegative partner for the last 6 months
2. No injection drug use

RISK DEFINITION B:

ALL OF THE FOLLOWING

1. No newly acquired higher risk associated STD in the last 6 months
2. No possibly safe or unsafe sex with a known HIV+ individual or an active injection drug user in the past 6 months
3. Unsafe sexual activity with two or fewer partners within the last 6 months
4. Possibly safe sexual activity with four or fewer partners within the last 6 months
5. No injection drug use in the last 1 year

RISK DEFINITION D:

ONE OR MORE OF THE FOLLOWING

1. A newly acquired higher risk-associated STD within the past 6 months.
2. Unsafe sexual activity with 4 or more partners with in the past 6 months
3. Possibly safe or unsafe sex with a known HIV+ individual in the past 6 months.
4. Possibly safe sexual activity with 12 or more partners in the past 6 months.
5. Any injection drug use in the last 1 year

RISK DEFINITION C:

ALL REMAINING INDIVIDUALS